Dr. Hamdy studies the cardiovascular benefits of short and long term weight reduction in obese individuals with and without type 2 diabetes. He also studies the role of body fat distribution in initiation and acceleration of cardiometabolic complications of obesity. His clinical research also evaluates the effect of weight reduction on circulating cytokines and body fact distribution. Dr. Hamdy and colleagues' research led to the first discovery that obese adults who lost 7 percent of their initial weight had significant improvement in their vascular endothelial function. This improvement may eventually prevent the progression of atherosclerosis and the subsequent risk of coronary artery disease and stroke.
Osama Hamdy, MD, PhD, FACE is the Medical Director of the Obesity Clinical Program, at Joslin Clinic and Director of Inpatient Diabetes Management. He is a Clinical Investigator and attending Adult Endocrinologist at Joslin Diabetes Center and Assistant Professor of Medicine at Harvard Medical School.
Dr. Hamdy is a co-investigator of 2 landmark studies; the National Diabetes Prevention Program and the Look AHEAD (Action for Health in Diabetes) Study. He translated the successful clinical research results of these lifestyle modification clinical trials into a clinical practice model through the initiation of the Why WAIT Program (Weight Achievement and Intensive Treatment), the world's first multidicplinary clinical practice model for diabetes weight management. Dr. Hamdy chaired the task force that developed the Joslin New Nutrition Guidelines and is a member of the Nutrition Guidelines Committee of the American Association of Clinical Endocrinologists (AACE) that created the AACE Nutrition Guidelines for Healthy Americans, the Guidelines for Obesity Management and the Guidelines for Bariatric Surgery.
Dr. Hamdy has over 100 peer-reviewed publications, book chapters and clinical proceedings about diabetes and obesity. He is a member of editorial review boards for several medical journals including JAMA, Diabetes Care, Expert Opinion Journals and Obesity Research.